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Are You Considering Weight-Loss Injections? A Comparative Guide to Currently Available Options

July 18, 202310 min read

They Sound Too Good to Be True, But is There a Catch?

Are you intrigued by the idea of weight loss injections? They seem to promise incredible transformations and a shortcut to shedding those extra pounds. However, it’s crucial to approach them with caution and understand both the potential benefits and risks involved.

While some people have experienced positive results with these injections, it’s important to know that they can also come with side effects and considerations. Additionally, many of these medications require strict diets and exercise routines, and some may only lead to modest weight loss of around 10%, which could be regained if you stop taking the medication.

Considering these factors, it’s worth exploring alternative options that prioritize long-term sustainability, don’t involve strict diets or intense workouts, and offer positive outcomes without negative side effects. In this guide, we’ll explore the world of weight loss injections, discussing their potential benefits while highlighting the importance of making informed decisions and finding sustainable approaches to weight loss.

Saxenda (liraglutide):
Saxenda, an injectable medication, is designed to mimic the hormone GLP-1, regulating appetite and food intake. It is FDA-approved for chronic weight management in individuals with obesity or overweight. Saxenda has shown effectiveness in reducing weight and improving obesity-related health conditions. 

Potential Side Effects Include:

  • headache

  • constipation

  • heartburn

  • runny nose, sneezing, or cough

  • tiredness

  • difficulty urinating or pain or burning on urination

  • injection site rash or redness

  • ongoing pain that begins in the upper left or middle of the stomach but may spread to the back

  • new or worsening depression

  • thinking about harming or killing yourself

  • unusual changes in mood or behavior

  • vomiting

  • nausea

  • diarrhea

  • clay-colored stools

  • yellow eyes or skin

  • heart pounding

  • fainting or feeling dizzy

  • swelling of the eyes, face, mouth, tongue, or throat

  • rash

  • itching

  • difficulty breathing or swallowing

Sources:
– Official website: Saxenda – www.saxenda.com
– U.S. National Library of Medicine: Liraglutide – medlineplus.gov/druginfo/meds/a611003.html

Liraglutide Warning Taken From The National Library of Medicine Website

Liraglutide injection may increase the risk that you will develop tumors of the thyroid gland, including medullary thyroid carcinoma (MTC; a type of thyroid cancer). Laboratory animals who were given liraglutide developed tumors, but it is not known if this medication increases the risk of tumors in humans. Tell your doctor if you or anyone in your family has or has ever had MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2; condition that causes tumors in more than one gland in the body). If so, your doctor will probably tell you not to use liraglutide injection. If you experience any of the following symptoms, call your doctor immediately: lump or swelling in the neck; hoarseness; difficulty swallowing; or shortness of breath.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain tests to check your body’s response to liraglutide injection.

Your doctor or pharmacist will give you the manufacturer’s patient information sheet (Medication Guide) when you begin treatment with liraglutide injection and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer’s website to obtain the Medication Guide.

Talk to your doctor about the risks of using liraglutide injection.

Wegovy (semaglutide):
Wegovy is a GLP-1 receptor agonist similar to Saxenda and is approved for chronic weight management in adults with obesity. By reducing appetite and increasing feelings of fullness, Wegovy has the potential for significant weight loss and improvement in obesity-related health conditions. 

Potential Side Effects Include: 

  • nausea

  • vomiting

  • diarrhea

  • abdominal pain

  • constipation

  • heartburn

  • burping

  • ongoing pain that begins in the upper left or middle of the stomach but may spread to the back, with or without vomiting

  • rash; itching; swelling of the eyes, face, mouth, tongue, or throat; or difficulty breathing or swallowing

  • decreased urination; or swelling of legs, ankles, or feet

  • vision changes

  • fainting or dizziness

  • pain in upper stomach; yellowing of skin or eyes; fever; or clay-colored stools (in those receiving semaglutide [Wegovy] for management of weight loss)

  • rapid heartbeat

Sources:
– Official website: Wegovy – www.wegovy.com
– U.S. National Library of Medicine: Semaglutide – medlineplus.gov/druginfo/meds/a618008.html

Ozempic (semaglutide):
Although Ozempic is primarily used for managing type 2 diabetes, it has also shown potential for weight reduction. This GLP-1 receptor agonist offers dual benefits for glycemic control and weight loss. 

Potential Side Effects Include: 

  • nausea

  • vomiting

  • diarrhea

  • abdominal pain

  • constipation

  • heartburn

  • burping

  • ongoing pain that begins in the upper left or middle of the stomach but may spread to the back, with or without vomiting

  • rash; itching; swelling of the eyes, face, mouth, tongue, or throat; or difficulty breathing or swallowing

  • decreased urination; or swelling of legs, ankles, or feet

  • vision changes

  • fainting or dizziness

  • pain in upper stomach; yellowing of skin or eyes; fever; or clay-colored stools (in those receiving semaglutide [Wegovy] for management of weight loss)

  • rapid heartbeat

Sources:
– Official website: Ozempic – www.ozempic.com
– U.S. National Library of Medicine: Semaglutide – medlineplus.gov/druginfo/meds/a618008.html

Semaglutide Warning Taken From the U.S. National Library of Medicine Website

Semaglutide injection may increase the risk that you will develop tumors of the thyroid gland, including medullary thyroid carcinoma (MTC; a type of thyroid cancer). Laboratory animals who were given semaglutide developed tumors, but it is not known if this medication increases the risk of tumors in humans. Tell your doctor if you or anyone in your family has or has ever had MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2; condition that causes tumors in more than one gland in the body). If so, your doctor will probably tell you not to use semaglutide injection. If you experience any of the following symptoms, call your doctor immediately: a lump or swelling in the neck; hoarseness; difficulty swallowing; or shortness of breath.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain tests to check your body’s response to semaglutide injection.

Your doctor or pharmacist will give you the manufacturer’s patient information sheet (Medication Guide) when you begin treatment with semaglutide injection and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer’s website to obtain the Medication Guide.

Talk to your doctor about the risks of using semaglutide injection.

Contrave (bupropion/naltrexone):
Contrave combines bupropion and naltrexone to aid in chronic weight management for individuals with obesity or overweight. Bupropion helps reduce appetite, while naltrexone counteracts the reward and reinforcement effects of food. Contrave offers potential weight loss benefits and a unique combination of mechanisms. 

Potential Side Effects Include:

 

Sources:
– Official website: Contrave – www.contrave.com
– U.S. National Library of Medicine: Naltrexone and Bupropion – medlineplus.gov/druginfo/meds/a619020.html

Bupropion Warning Taken From The U.S. National Library of Medicine Website

This medication contains bupropion, the same active ingredient as some antidepressant medications (Wellbutrin, Aplenzin) and a medication used to help people stop smoking (Zyban). A small number of children, teenagers, and young adults (up to 24 years of age) who took antidepressants (‘mood elevators’) such as bupropion during clinical studies became suicidal (thinking about harming or killing oneself or planning or trying to do so). Children, teenagers, and young adults who take antidepressants to treat depression or other mental illnesses may be more likely to become suicidal than children, teenagers, and young adults who do not take antidepressants to treat these conditions. The combination of naltrexone and bupropion is not approved for use in children under 18 years of age.

You should know that your mental health may change in unexpected ways when you take the combination of naltrexone and bupropion even if you are an adult over 24 years of age. You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; anxiety or panic attacks; difficulty falling asleep or staying asleep; aggressive, angry, or violent behavior; irritability; acting without thinking; severe restlessness; abnormal thoughts or sensations; feeling that people are against you; hallucinations (seeing things or hearing voices that do not exist); feeling confused; frenzied abnormal excitement; or any other sudden or unusual changes in behavior. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own.

Your healthcare provider will want to see you often while you are taking the combination of naltrexone and bupropion, especially at the beginning of your treatment. Be sure to keep all appointments for office visits with your doctor.

Your doctor or pharmacist will give you the manufacturer’s patient information sheet (Medication Guide) when you begin treatment with the combination of naltrexone and bupropion and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) or the manufacturer’s website to obtain the Medication Guide.

Talk to your doctor about the risks of taking the combination of naltrexone and bupropion.

In conclusion, weight loss injections such as Saxenda, Wegovy, Ozempic, and Contrave offer promising possibilities for individuals seeking to lose weight, however while these medications have demonstrated potential benefits in reducing weight and improving obesity-related health conditions, it is important to consider certain factors.

Most all weight loss injections may come with certain drawbacks, such as the cost of treatment and the need for regular injections to keep up the weight loss. These factors can make the long-term use of these medications challenging for some individuals. It is crucial to assess the financial implications and the feasibility of adhering to a treatment plan that may require frequent medical visits, strict diet and exercise requirements, and all the above mentioned potential side effects.

In light of these considerations, it is worth exploring alternative approaches to weight loss. However, it is important to note that not all solutions require medications or invasive procedures. If there was a way you could achieve weight loss without any negative side effects and continue to enjoy the foods you love, wouldn’t that be ideal? What if you could implement simple lifestyle changes that lead to sustainable results without the need for ongoing injections or costly treatments?

By adopting a holistic approach that focuses on balanced nutrition, regular physical activity, and mindful lifestyle habits, you can achieve meaningful and lasting weight loss. Making gradual changes to your eating habits, incorporating enjoyable physical activities, and seeking support from professionals can pave the way for sustainable success.

Ultimately, the decision regarding weight-loss treatments should be made in consultation with healthcare professionals who can provide personalized advice based on your unique needs and goals. Your health and well-being should always be the top priority.

Remember, there is no one-size-fits-all solution, and what works for one person may not work for another. Embrace your individual journey, stay informed, and make choices that align with your long-term health and happiness.

If you have any further questions or require additional information, don’t hesitate to consult with your healthcare provider for accurate and up-to-date information for your own unique situation.

If there was a way you could lose weight that didn’t have any negative side effects that would be a good thing right?

If you could continue losing weight while still being allowed to eat the foods you enjoy that would be even better would it not?

And if there was something that you could do for only a short period of time that would make sustainable changes in your weight without needing to use potentially harmful and expensive weight-loss injections every week, and possibly even get better results overall, that would be exactly what you’re looking for right?

Click the big blue button below to schedule your Virtual Skinny Jab™ Weight-Loss Planning Session.

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Michael D. Milson

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